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| 27.07.2022 | 02:10 | Estudiantes de Caseros | - | Brown de Adrogué | 1:0 (0:0) | |
| 20:00 | Temperley | - | Alvarado | 0:0 (0:0) | ||
| 20:00 | Flandria | - | Almagro | 0:3 (0:0) | ||
| 20:00 | Gimnasia de Jujuy | - | Nueva Chicago | 2:0 (1:0) | ||
| 20:00 | Villa Dálmine | - | Quilmes | 2:0 (0:0) | ||
| 20:05 | Gimnasia de Mendoza | - | Instituto de Córdoba | 2:0 (0:0) | ||
| 20:30 | San Telmo | - | Agropecuario Argentino | 0:0 (0:0) | ||
| 28.07.2022 | 00:00 | Güemes de SdE | - | Mitre de SdE | 1:1 (1:1) | |
| 00:30 | Atlanta | - | Defensores de Belgrano | 0:2 (0:0) | ||
| 01:00 | Almirante Brown | - | Deportivo Maipú | 2:1 (2:1) | ||
| 01:05 | All Boys | - | Sacachispas | 2:1 (1:1) | ||
| 01:30 | Ramón Santamarina | - | Chacarita Juniors | 2:1 (2:1) | ||
| 02:00 | Chaco For Ever | - | Tristan Suárez | 1:0 (1:0) | ||
| 02:35 | Belgrano de Córdoba | - | Independiente Rivadavia | 1:1 (0:0) | ||
| 20:35 | San Martín de San Juan | - | San Martín de Tucumán | 0:2 (0:0) | ||
| 23:35 | Atlético Rafaela | - | Guillermo Brown | 4:1 (2:0) | ||
| 29.07.2022 | 02:35 | Deportivo Morón | - | Estudiantes de Río Cuarto | 2:2 (1:1) | |
| 31.08.2022 | 20:00 | Deportivo Riestra | - | Ferro Carril Oeste | 1:0 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Belgrano de Córdoba | 25 | 17 | 6 | 2 | 30:13 | 17 | 57 |
| 2 |
|
San Martín de Tucumán | 25 | 13 | 10 | 2 | 32:15 | 17 | 49 |
| 3 |
|
Instituto de Córdoba | 25 | 13 | 8 | 4 | 31:18 | 13 | 47 |
| 4 |
|
All Boys | 25 | 11 | 12 | 2 | 37:20 | 17 | 45 |
| 5 |
|
Gimnasia de Mendoza | 25 | 11 | 10 | 4 | 30:12 | 18 | 43 |
| 6 |
|
Almagro | 26 | 12 | 6 | 8 | 26:22 | 4 | 42 |
| 7 |
|
Estudiantes de Río Cuarto | 26 | 10 | 11 | 5 | 30:25 | 5 | 41 |
| 8 |
|
Independiente Rivadavia | 25 | 10 | 8 | 7 | 33:24 | 9 | 38 |
| 9 |
|
San Martín de San Juan | 26 | 11 | 5 | 10 | 35:28 | 7 | 38 |
| 10 |
|
Defensores de Belgrano | 25 | 9 | 11 | 5 | 28:21 | 7 | 38 |
| 11 |
|
Brown de Adrogué | 25 | 10 | 8 | 7 | 29:23 | 6 | 38 |
| 12 |
|
Chaco For Ever | 26 | 8 | 13 | 5 | 27:20 | 7 | 37 |
| 13 |
|
Deportivo Riestra | 25 | 8 | 12 | 5 | 23:20 | 3 | 36 |
| 14 |
|
Deportivo Madryn | 25 | 8 | 11 | 6 | 33:26 | 7 | 35 |
| 15 |
|
Chacarita Juniors | 25 | 9 | 8 | 8 | 37:32 | 5 | 35 |
| 16 |
|
Estudiantes de Caseros | 26 | 9 | 8 | 9 | 21:22 | -1 | 35 |
| 17 |
|
Deportivo Maipú | 26 | 7 | 13 | 6 | 29:24 | 5 | 34 |
| 18 |
|
Gimnasia de Jujuy | 25 | 8 | 8 | 9 | 27:31 | -4 | 32 |
| 19 |
|
Guillermo Brown | 25 | 9 | 5 | 11 | 21:27 | -6 | 32 |
| 20 |
|
Agropecuario Argentino | 25 | 6 | 13 | 6 | 22:22 | 0 | 31 |
| 21 |
|
Güemes de SdE | 25 | 7 | 9 | 9 | 20:20 | 0 | 30 |
| 22 |
|
Almirante Brown | 25 | 6 | 12 | 7 | 28:31 | -3 | 30 |
| 23 |
|
Ferro Carril Oeste | 25 | 7 | 9 | 9 | 20:26 | -6 | 30 |
| 24 |
|
Deportivo Morón | 25 | 5 | 14 | 6 | 17:16 | 1 | 29 |
| 25 |
|
Mitre de SdE | 25 | 7 | 8 | 10 | 25:28 | -3 | 29 |
| 26 |
|
Quilmes | 25 | 6 | 10 | 9 | 28:32 | -4 | 28 |
| 27 |
|
Alvarado | 26 | 6 | 9 | 11 | 25:40 | -15 | 27 |
| 28 |
|
Atlético Rafaela | 26 | 5 | 11 | 10 | 27:31 | -4 | 26 |
| 29 |
|
Atlanta | 26 | 5 | 11 | 10 | 19:25 | -6 | 26 |
| 30 |
|
Temperley | 25 | 5 | 11 | 9 | 20:28 | -8 | 26 |
| 31 |
|
Nueva Chicago | 26 | 5 | 10 | 11 | 26:37 | -11 | 25 |
| 32 |
|
San Telmo | 25 | 5 | 9 | 11 | 23:39 | -16 | 24 |
| 33 |
|
Tristan Suárez | 25 | 5 | 8 | 12 | 27:31 | -4 | 23 |
| 34 |
|
Sacachispas | 25 | 3 | 14 | 8 | 18:27 | -9 | 23 |
| 35 |
|
Villa Dálmine | 25 | 4 | 11 | 10 | 29:43 | -14 | 23 |
| 36 |
|
Flandria | 25 | 4 | 9 | 12 | 25:36 | -11 | 21 |
| 37 |
|
Ramón Santamarina | 26 | 4 | 9 | 13 | 18:41 | -23 | 21 |
| Promotion | |
| Play-off | |
| Play-off | |
| Relégation |
